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				###	Description	####
	

First download the GNG package (GNG_1.0.tar.gz). Be sure to chosse the appropriate version for you operating system.

Contained therein is an R package for a robust unified method for analyzing both methylation and gene expression data. This method has two unique features: It allows for a flexible choice of the component that models non-biological variation and small biases in the data; It uses a robust procedure for parameter estimation and probe/gene classification. By doing so, the data are more fully utilized, and probes with 
different intensities but the same log ratio can be distinguished

			
				###	Installation	####


You must have the R (>2.7) installed. You can obtain the R instalation for you operating system at 

Windows: http://cran.r-project.org/bin/windows/base/release.htm
OS X: http://cran.r-project.org/bin/macosx/R-2.7.0.dmg
Linux: http://cran.r-project.org/bin/linux/

Instructions for installing R for your given operating system can be found at http://cran.r-project.org/

##Windows##

1. Open your RGui
2. Select Packages -> Install package(s) from local zip file...
3. Direct the browser to GNG_1.0.zip (It should be in the same folder as this ReadMe file.) and click "open"
4. To load the package in R, type "library(GNG)" at the command prompt.
5. To read the help files and for examples associated with GNG, your can type "help('GNG')" at the command line.

##Macintosh##

1. Open your RGui
2. Select Packages & Data -> Package Installer
3. From the drop down menu in the top left corner of the new window, select "Local Binary Package" and click the Install button (bottom right corner).
4. Direct the browser to GNG_1.0.tar.gz (It should be in the same folder as this ReadMe file.) and click "open".
4. To load the package in R, type "library(GNG)" at the command prompt.
5. To read the help files and for examples associated with GNG, your can type "help('GNG')" at the command line.


##Linux##

1. At the command line enter "R CMD INSTALL PACKAGE_DIRECTORY/GNG_1.0.tar.gz" where PACKAGE_DIRECTORY is the chain of folders containing GNG_1.0.tar.gz that you have just downloaded
2. Open R by typing "R" at the command line.
3. To load the package in R, type "library(GNG)" at the command prompt.
4. To read the help files and for examples associated with GNG, your can type "help('GNG')" at the command line.