1:00-2:00 Small RNAs in germ granules
Wen Tang,
Department of Biological Chemistry & Pharmacology
The Tang lab investigates fundamental controls of germ cell development using the nematode worm C. elegans as a model system. We focus on piRNAs, a class of germline small RNAs that defend genome against invasive nucleic acid. We are exploring the mechanisms of piRNAs biogenesis and their role in repressing endogenous genes and transposons. We study germ granules, mysterious RNA-rich organelles that are required for germ cell maintenance. We are taking advantage of the state-of-the-art genomics, imaging and mass spectrometry approaches to investigate the composition and function of germ granules
Last update: 08/16/2021, Ralf Bundschuh